Table 4. Cytokine Profiles For Trauma Patients With and Without Severe Head Injuries Stratified by In-Hospital Mortality.
Cytokine | Severe head injury (n=335) |
No severe head injury (n=687) |
||||
---|---|---|---|---|---|---|
Survivor (n=687) (n=290) |
Mortality (n=45) |
p Value | Survivor (n=623) |
Mortality (n=64) |
p Value | |
IL-1 | 2.7 [4.4] | 2.7 [5.1] | 0.98 | 2.7 [2.5] | 2.7 [3.6] | 0.55 |
IL-2 | 4.2 [11.4] | 3.1 [13.2] | 0.83 | 2.8 [10.2] | 2.7 [4.7] | 0.50 |
IL-4 | 30.3 [152.8] | 108 [439.2] | 0.001 | 31.2 [190.4] | 112.7 [393.3] | 0.001 |
IL-5 | 2.7 [2.8] | 2.7 [6.9] | 0.33 | 2.7 [1.6] | 2.7 [1.7] | 0.71 |
IL-6 | 116.1 [227.4] | 162.5 [307.5] | 0.07 | 162.0 [335.8] | 247.4 [827.6] | 0.003 |
IL-8 | 22.3 [45.5] | 28.7 [56.8] | 0.11 | 33.9 [53.2] | 55.9 [126.9] | 0.003 |
IL-10 | 48.0 [91.5] | 50.8 [139.4] | 0.69 | 53.1 [110.3] | 66.9 [112.2] | 0.21 |
IL-12 | 3.4 [10.1] | 3.2 [12.6] | 0.85 | 2.7 [5.4] | 2.7 [5.2] | 0.70 |
IFN | 4.5 [11.5] | 4.1 [15.1] | 0.85 | 3.0 [7.5] | 2.7 [5.9] | 0.84 |
GMCSF | 5.1 [8.8] | 4.9 [9.2] | 0.84 | 3.6 [6.3] | 4.9 [11.2] | 0.20 |
TNF-α | 4.5 [6.0] | 4.8 [9.0] | 0.38 | 5.2 [7.2] | 7.5 [10.1] | 0.01 |