Table 3.

Multivariate analysis of HBV mutations affecting HCC development

Variables	OR	95% CI	P value
Older age, years	1.094	1.069–1.120	<0.001
Male	1.306	0.752–2.267	0.344
G1896A	2.725	1.260–5.894	0.011
C1653T	5.278	1.182–23.575	0.029
BCP	1.502	0.821–2.746	0.186
BCP + C1653T	5.396	1.106–26.319	0.037
BCP + G1896A	1.326	0.503–3.495	0.569
G1896A + C1653T	1.505	0.400–5.658	0.545
G1896A + T1753V	1.220	0.426–3.495	0.712
C1653T + T1753V	2.669	0.701–10.163	0.150

OR, odds ratio; CI, confidence interval; BCP, basal core promoter A1762T/G1764A double mutation.