Figure.8. MMP-9 is involved in the ColVIa turnover in the inner ear.
(A) Immunostaining results demonstrate ColVIa expression in the cochlear sections from WT, WT + FA, CBS+/−, CBS+/−+ FA and MMP-9 Knock out group. n=4; three sections from each group were scanned for digital data analysis. *Notice: MMP-9 Knockout mice cochlea was stained for Col4a showed highly reduced deposition for the collagen 4A. (B) Bar diagram represents quantification of immunostaining using image pro software. P<0.001 vs WT,#P<0.001 vs CBS+/−; $ P<0.001 vs CBS+/−; n=4 animals/ group.