Table 3.
Effect of treatment on HbA1c evolution in relation to presence of chronic comorbidity and medication, obtained using multiple logistic regression analysis. Results are adjusted for age and sex
| Diet only, OR (95% CI) | Oral drugs, OR (95% CI) | Combination, OR (95% CI) | Insulin only, OR (95% CI) | |
|---|---|---|---|---|
| No comorbidity, no medication | 1.00 | 1.39 (1.16 to 1.66) | 1.36 (1.07 to 1.74) | 0.96 (0.67 to 1.37) |
|
| ||||
| Comorbidity | ||||
| Joint disorders | 1.04 (0.71 to 1.53) | 1.57 (1.00 to 2.47) | 1.32 (0.73 to 2.36) | 2.51 (1.05 to 6.02) |
| Respiratory disorders | 0.81 (0.51 to 1.27) | 1.55 (0.92 to 2.62) | 2.00 (0.97 to 4.11) | 3.06 (1.05 to 8.91 |
|
| ||||
| Respiratory + joint disorders | 1.34 (1.11 to 1.69) | |||
|
| ||||
| Medication | ||||
| Corticosteroids | 1.31 (1.13 to 1.52) | 1.39 (1.16 to 1.66) | 1.35 (1.06 to 1.72) | 0.97 (0.68 to 1.38) |
| NSAID | 1.34 (1.14 to 1.58) | 1.36 (1.13 to 1.62) | 1.34 (1.05 to 1.70) | 0.97 (0.68 to 1.39) |
| Corticosteroids + NSAID | 1.41 (1.21 to 1.64) | 1.38 (1.16 to 1.65) | 1.36 (1.07 to 1.73) | 0.99 (0.69 to 1.41) |
|
| ||||
| Comorbidity + medication | ||||
| Respiratory + joint disorders + NSAID | 0.95 (0.57 to 1.57) | 1.53 (0.85 to 2.75) | 1.55 (0.69 to 3.50) | 4.32 (1.23 to 15.13) |
BMI did not significantly add to the modelling. Reference group for all OR: patients with no medication, no comorbidity, diet only. No interaction between treatment effect and treatment group. All results given in bold are statistically significant. BMI = body mass index. NSAID = non-steroidal anti-inflammatory drug. OR = odds ratio.