Table 3.
Percentage Change in Geometric Mean Breast Milk Fatty Acid Concentration for a 1-Point Increase in Center for Epidemiologic Studies Depression Scale Score
| Fatty Acida | Unadjusted Model (95% Confidence Interval)b | Adjusted Model (95% Confidence Interval)c |
|---|---|---|
| < 20 wk, pregnancy | ||
| Total ω-3 | −0.67 (−1.27, −0.07) | −0.55 (−1.21, 0.13) |
| Total ω-6 | −0.21 (−0.57, 0.16) | −0.30 (−0.69 1.01) |
| ω-6:ω-3 | 0.04 (−0.03, 0.10) | 0.01 (−0.06. 0.9) |
| Eicosapentaenoic acid | −0.86 (−1.73, 0.04) | −0.31 (−1.28, 0.67) |
| Docosahexaenoic acid | −1.32 (−2.19, −0.46) | −1.15 (−2.12, −0.19) |
| 24–29 wk, pregnancy | ||
| Total ω-3 | −0.32 (−0.90, 0.27) | −0.14 (−0.76, 0.48) |
| Total ω-6 | −0.07 (−0.41, 0.26) | −0.19 (−0.55, 0.16) |
| ω-6:ω-3d | 0.2 (−0.04, 0.08) | −0.01 (−0.08, 0.05) |
| Eicosapentaenoic acid | −0.73 (−1.57, 0.12) | −0.18 (−1.05, 0.70) |
| Docosahexaenoic acid | −0.69 (−1.54, 0.16) | −0.27 (−1.16, 0.61) |
a
Regression models included log-transformed fatty acid variables. The results presented were backtransformed.
b
Unadjusted models included a variable for the laboratory analyzed the sample.
c
Adjusted models included education, smoking, maternal age, parity, income, estimated daily dietary intake of ω-3 or ω-6 fatty acids (depending on the model), and laboratory.
d
The ω-6:ω-3 ratio was not log-transformed when included in regression models. Results can be interpreted as a 1-point increase in Center for Epidemiologic Studies Depression Scale score corresponding to a 1-unit increase in ω-6:ω-3.