FIG. 3.

A: Rac1-GTP binding in human soleus (SOL) and gastrocnemius (Gast) in the basal state and after 45 min of inclined walking at ∼69% Vo_{2 peak} (n = 5–9). B: Exercise-stimulated fold changes from basal in soleus (SOL) and gastrocnemius (Gast). C: Bar graph and representative Western blot analysis of p-Rac1^Ser71 in response to exercise in human soleus and gastrocnemius muscle (n = 5–9). D: Bar graph and Western blot analysis of p-PAK^Thr423 in response to exercise in human soleus and gastrocnemius muscle (n = 5–9). Statistical significance compared with basal is indicated by *P < 0.05; **P < 0.01. Values represent mean ± SEM.