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. 2013 Mar 14;62(4):1345–1350. doi: 10.2337/db12-0747

FIG. 1.

FIG. 1.

Diabetes-free survival in persistently Ab+ FDRs at baseline (n = 288) stratified according to HLA-A*24, HLA-DQ2/DQ8, and IA-2A/ZnT8A status: presence of HLA-A*24, solid orange line; absence of HLA-A*24, broken orange line (A); presence of HLA-DQ2/DQ8, solid green line; absence of HLA-DQ2/DQ8, broken green line (B); presence of IA-2A and/or ZnT8A, solid purple line; absence of IA-2A and ZnT8A, broken purple line (C); presence of HLA-A*24 and HLA-DQ2/DQ8, solid red line; presence of HLA-DQ2/DQ8 and absence of HLA-A*24, solid green line; presence of HLA-A*24 and absence of HLA-DQ2/DQ8, broken red line; absence of HLA-DQ2/DQ8 and of HLA-A*24, broken green line (D); presence of HLA-A*24 and (IA-2A and/or ZnT8A), solid blue line; presence of (IA-2A and/or ZnT8A) and absence of HLA-A*24, solid yellow line; presence of HLA-A*24 and absence of (IA-2A and ZnT8A), broken blue line; absence of IA-2A, ZnT8A and of HLA-A*24, broken yellow line (E); presence of IA-2A and/or ZnT8A and HLA-DQ2/DQ8, solid fuchsia line; presence of IA-2A and/or ZnT8A and absence of HLA-DQ2/DQ8, solid cyan line; presence of HLA-DQ2/DQ8 and absence of IA-2A and ZnT8A, broken fuchsia line; absence of IA-2A, ZnT8A, and HLA-DQ2/DQ8, broken cyan line (F). The numbers in each panel indicate the number of events for each arm (total number at study entry). P by log-rank test.