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Metabolic phenotype of HFD feeding. A: Body weight gain after HFD treatment. B: IPGTT before and 12 weeks into the HFD. C: IPinsTT before and 12 weeks into the HFD. D: Fasted blood glucose levels before and 12 weeks into the HFD. Data are presented as means ± SEM. *P < 0.05, **P < 0.01, and ***P < 0.001 for a chance difference vs. controls using the Student unpaired t test.
