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. 2013 Jan 29;24(3):283–294. doi: 10.1089/hum.2012.162

Table 1.

Total Production of hFIX Protein for 24 Hours

Days after transduction MOI hFIX protein (ng) per 105 cells Cumulative number of cells (×105) hFIX protein (ng) from cumulative cells
4 1 21.28±5.30 2.93±0.60 60.37±3.24a
  5 261.57±45.23 2.08±0.33 535.49±37.69a
  10 494.99±93.79 1.73±0.20 843.84±65.40a
  30 N/A N/A N/A
8 1 27.81±5.08 4.15±1.15 111.63±14.45a
  5 245.23±59.24 2.71±0.74 641.15±80.28a
  10 383.78±80.05 2.40±0.80 885.83±138.03a
  30 N/A N/A N/A
19 1 9.57±2.58 6.26±1.72 57.87±11.86a
  5 81.26±22.14 4.15±1.77 316.31±93.21
  10 103.46±20.32 3.06±0.54 324.15±124.48
  30 N/A N/A N/A
28 1 24.52±13.76 12.03±3.89 270.87±128.77
  5 119.49±42.86 5.94±2.11 744.11±493.55
  10 148.97±49.51 5.05±0.78 762.32±326.91
  30 514.50±191.43 1.03±0.42 478.57±42.42

hFIX, human factor IX; MOI, multiplicity of infection; N/A, not applicable.

Note: Data are expressed as mean values±SD.

a

p<0.05 versus the other groups in the same day after transduction (n=3).