Table 3.
Distribution of Allelic and Genotypic Frequencies of CTLA 4 3′UTR (AT)n in Four Tested Cohorts
| Case (n) | Allele | Case no. (f) | Control no. (f) | Chi square | p-Value |
|---|---|---|---|---|---|
| SLE (420) | 6 | 376 (0.90) | 1.18 | 0.28 | |
| 15 | 44 (0.10) | ||||
| RA (224) | 6 | 200 (0.89) | 6–422 (0.87) | 0.63 | 0.43 |
| 15 | 24 (0.11) | 15–62 (0.13) | |||
| OP (76) | 6 | 66 (0.87) | 0.01 | 0.92 | |
| 15 | 10 (0.13) |
| Case (n) | Genotype | Case no. (f) | Control no. (f) | Chi square | p-Value |
|---|---|---|---|---|---|
| SLE (210) | 182 (0.87) | 2.64 | 0.1 | ||
| RA (112) | 6/6 | 94 (0.84) | 196 (0.81) | 0.45 | 0.5 |
| OP (38) | 30 (0.79) | 0.09 | 0.76 | ||
| SLE (210) | 16 (0.08) | 0.17 | 0.68 | ||
| RA (112) | 15/15 | 6 (0.05) | 16 (0.07) | 0.21 | 0.65 |
| OP (38) | 2 (0.13) | 0.09 | 0.75 | ||
| SLE (210) | 12 (0.06) | 5.9 | 0.01 | ||
| RA (112) | 15/6 | 12 (0.11) | 30 (0.12) | 0.52 | 0.47 |
| OP (38) | 6 (0.16) | 0.34 | 0.56 |
Bold value indicates significance.