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. 2013 Mar 27;9(3):e1003212. doi: 10.1371/journal.pgen.1003212

Table 3. Analysis of associations with breast and ovarian cancer risk simultaneously (competing risks analysis) for SNPs found to be associated with breast or ovarian cancer.

SNP, Chr, Position, Allele1/Allele2 Unaffected (Allele2 Freq) Ovarian Cancer (Allele2 Freq) Breast Cancer (Allele2 Freq) Ovarian Cancer Breast Cancer
HR (95% CI) P HR (95% CI) P
SNPs found to be associated with breast cancer risk.
rs2290854, 1q32, 202782648, G/A 5473 (0.31) 1618 (0.31) 7259 (0.33) 1.08 (0.99–1.18) 0.08 1.14 (1.09–1.20) 2.7×10−8
rs6682208, 1q32, 202832806, G/A 5471 (0.32) 1618 (0.33) 7260 (0.34) 1.08 (1.00–1.18) 0.06 1.13 (1.08–1.19) 1.2×10−7
rs11196174, 10q25.3, 114724086, A/G 5471 (0.28) 1618 (0.29) 7257 (0.31) 1.07 (0.98–1.16) 0.16 1.14 (1.08–1.19) 3.2×10−7
rs11196175, 10q25.3, 114726604, A/G 5465 (0.28) 1615 (0.29) 7247 (0.31) 1.07 (0.97–1.16) 0.16 1.14 (1.08–1.19) 3.9×10−7
SNPs found to be associated with ovarian cancer risk
rs17631303, 17q21, 40872185, A/G 5445 (0.19) 1610 (0.22) 7215 (0.19) 1.26 (1.14–1.39) 1.0×10−5 1.02 (0.96–1.08) 0.52
rs183211, 17q21, 42143493, G/A 5473 (0.23) 1618 (0.26) 7260 (0.23) 1.25 (1.14–1.38) 3.5×10−6 1.02 (0.97–1.08) 0.42
rs4691139, 4q32.3, 166128171, A/G 5473 (0.48) 1617 (0.53) 7269 (0.48) 1.21 (1.12–1.31) 2.8×10−6 0.98 (0.93–1.02) 0.28