Table 1.

Stage-Specific Human Embryonic microRNAs in hESC Neuronal Lineage-Specific Progression.

	miRNA Group	Highest Expression in Cells	Expression Levels in hESCs	Expression Levels in hNuPs	Expression Levels in hNus	miRNAs
Human Pluripotence-Associated miRNAs	Group 1	hESC	+++	−	−	hsa-miR-302b, 302a, 302a*, 302d, 302c
	Group 2	hESC	+++	+	+	hsa-miR-373, 3178, 363, 3170
	Group 3	hESC	+++	+++/++	+	hsa-miR-574-5p, 20a, 20b, 17, 4298, 106a, 3141, 1246, 1268, 221, 92a, 574-3p, 182, 466, 638, 3185, 762, 4281
	Group 4	hESC	+++	++	+	hsa-miR-3196, 1915, 222, 107, 663, 92b, 15b
Human Neuronal Progenitor-Associated miRNAs	Group 1	hNuP	−	+++	++/+	hsa-miR-10b, 10a, 224
	Group 2	hNuP	+	+++	+	hsa-miR-9, 125a-5p, 181d, 4324
	Group 3	hNuP	++	+++	+	hsa-miR-26b, 181b, 25, 31, 21, 335, 1275
	Group 4	hNuP	++	+++	++	hsa-miR-27b, 93, 99b, 100
Human Neuron-Associated miRNAs	Group 1	hNu	+/−	+	+++	hsa-miR-744, 128, 138, 34a, 22, 143, 124, 24, 145, 199a-5p, 324-5p, 152
	Group 2	hNu	+	+/−	+++	hsa-miR-423-5p, 210, 140-3p, 708, 455-3p, 206, 720, 3195, 1280
	Group 3	hNu	+	++	+++	hsa-miR-let-7g, let-7e, let-7b, let-7a, let-7c, let-7i, let-7f, let-7d, 9*, 30e, 99a
	Group 4	hNu	++	+++/++	+++	hsa-miR-27a, 320d, 320b, 320c, 320e, 125b, 181a, 199a-3p, 30d, 16, 151-5p, 320a, 361-5p, 214

^*See human pluripotence-associated miRNA groups in figure 4, human neuronal progenitor-associated miRNA groups in figure 5, and human neuronal-associated miRNA groups in figure 6.