Figure 5. Repressive nucleoprotein complexes remain weakly expressed in hESC lineage-specific derivatives.
The chromatin depositions of SIRT1, SUV39H1, Brm, and me-H3K9 were significantly increased in CNS-D hNSCs, compared to those expressed at low levels in hESC-I hNuPs and hESC-D hNSCs, suggesting that CNS-derived tissue-resident hNSCs had acquired a more silenced chromatin. Scale bars: 2 μm.