Fig. 1.
Endogenous 3-iodothyronamine (T1AM) is thought to arise from enzymatic decarboxylation and deiodination of thyroxine (T4). Chemical structures for T1AM and its proposed precursor T4 are shown in (A). The positive mode electrospray ionization (ESI) MS profile for T1AM exhibited abundant [M+H]+ m/z 356 ion (B) that fragmented with MS/MS to give dominant [M+H-NH3]+ m/z 339 and [M+H-NH3-I]+ m/z 212 products ions (C).