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. 2013 Mar 27;8(3):e60643. doi: 10.1371/journal.pone.0060643

Figure 2. Diphtheria toxin mediated depletion of B cells in B-DTR mice.

Figure 2

The mice were treated once daily for 4 days with a dose of 25 ng/g body weight of diphtheria toxin. The decrease of B cells in comparison to T cells is shown in spleen, lymph nodes, bone marrow and peritoneal cavity; dot blots in the left panel and the corresponding bar charts in the right panel.