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. 2013 Mar 27;8(3):e60642. doi: 10.1371/journal.pone.0060642

Figure 2. LPS-induced podosome disassembly is not affected by SWAP-70 deficiency in DCs.

Figure 2

(A) Swap-70+/+ and Swap-70–/– DCs were treated with or without LPS for 60 min. Cells were stained with anti-Vinculin FITC (green), rhodamine phalloidin for F-actin (red), and DAPI for the nucleus (blue) and analyzed by confocal laser scanning microscopy. (B) Quantification of the number of DCs exhibiting podosome clusters with and without LPS treatment for 60 min. Graph indicates the number of cells with podosomes after LPS treatment relative to control (without LPS treatment). Mean values of 3 independent experiments with error bars indicating +SD are shown. N.S. denotes not significant.