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. 2013 Mar 27;8(3):e58848. doi: 10.1371/journal.pone.0058848

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© 2013 Li et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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NRK-52E cells were incubated with curcumin at the indicated dose for 12 hours followed by treatment with TGF-β1 for 36 hours(PAI-1, p-PPARγ and PPARγ) or 30 min(P-Smad2 and P-Smad3). (A) Western blotting analysis for PAI-1 expression. (B) Western blotting analysis for p-Smad2 and p-Smad3 expression. (C) Western blotting analysis for PPARγ and p-PPARγ expression.