Table 2. DNA methylation immunostaining (im) intensity in E17 hippocampus.
a. NE | b. IM | c. CA1 | |||||||
E17 | Chow | PF | Alc | Chow | PF | Alc | Chow | PF | Alc |
5mC-im | 168.1±5.3 | 152.1±3.2? | 150.9±6.9* | 139.9±5.7 | 132.3±9.8 | 159.0±5.3* # | 157.8±6.4 | 151.8±11.7 | 173.7±1.8* |
5hmC-im | 116.9±6.4 | 127.2±3.6 | 84.4±5.4* # | 113.52±5.7 | 134±5.2? | 112.1±4.8# | 144.7±2.6 | 163.6±3.6? | 167.1±3.0** |
P<0.05, **P<0.005 (Alc vs Chow); #P<0.05 (Alc vs PF); ?P<0.05 (PF vs Chow). N = 4 each. Data presented as Mean±SEM. NE:neuroepithelial layer; IM: intermediate zone.