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. 2013 Mar 27;8(3):e59630. doi: 10.1371/journal.pone.0059630

Figure 2. Sphingolipid concentration in selected tissues of inducible Sgpl1-deficient mice.

Figure 2

Two weeks after tamoxifen induction, tissues of Sgpl1Flox/Flox Cre+/− mice (open bars) and of Sgpl1Flox/Flox Cre−/− controls (filled bars) were obtained (n = 5/group). Tissues were extracted and sphingolipids were quantified by LC/MS. A, B, S1P; C, D, Sph; E, C16-ceramide. A, C, and E show absolute concentrations per weight of tissue; B and D show fold increase in inducible KO mice.