Figure 9. Diminished MOG-specific recall response of T-cells from inducible Sgpl1-deficient mice.

CD4-positive T cells purified from Sgpl1Flox/Flox Cre+/− and Sgpl1Flox/Flox Cre−/− mice on day 10 after MOG-induction were restimulated with MOG35–55 peptide in the presense of APCs; proliferation and IFNγ secretion was measured. Data from one representative experiment out of three independent studies are shown.