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. 2013 Mar 27;8(3):e59607. doi: 10.1371/journal.pone.0059607

Table 5. Genotypic analyses of SNPs with Cutaneous Melanoma risk association.

Non-adjusted Adjusted* Enlarged sample
SNP Statistical model OR (CI 95%) p-value OR (CI 95%) p-value OR (CI 95%) p-value
rs12512631 Genotypic 1.29 (1.04–1.60) 0.019 1.32 (1.01–1.72) 0.041 1.11 (0.96–1.28) 0.153
Dominant 1.63 (1.23–2.17) 7×10 4 1.71 (1.20–2.45) 3×10 3 1.28 (1.05–1.56) 0.012
Recessive 0.94 (0.61–1.45) 0.774 0.94 (0.55–1.60) 0.809 0.90 (0.68–1.19) 0.458
rs222016 Genotypic 1.30 (0.95–1.77) 0.102 1.23 (0.83–1.82) 0.312 1.11 (0.92–1.35) 0.277
Dominant 1.37 (0.98–1.93) 0.068 1.30 (0.85–1.98) 0.222 1.22 (0.97–1.52) 0.083
Recessive 0.95 (0.31–2.93) 0.929 0.65 (0.14–3.09) 0.586 0.65 (0.35–1.20) 0.168

Bold denotes statistically significant results.

OR (CI 95%) means Odds Ratio and its 95% confidence interval.

*

Adjusted for eye colour, hair colour, skin colour, lentigines, number of naevi and childhood sunburn.

The enlarged sample makes a total of 684 controls and 1045 cases.