Figure 1. PTB is associated with decreased spontaneous production of Type 1, 2, 17 and immunoregulatory cytokines.
Whole blood from PTB, TBL and LTB individuals was stimulated with media alone for 72 h, and levels of (A) Type 1 cytokines IFNγ, TNFα and IL-2; (B) Type 2 cytokines IL-4, IL-5, and IL-13; (C) Type 17 cytokines IL-17A, IL-17F and IL-22 and (D) Immunoregulatory cytokines IL-10 and TGFβ were measured by ELISA. Results are shown as scatterplots with each dot representing a single individuals. P values were calculated using the Kruskal-Wallis test with Dunn's multiple comparisons (* p<0.05, ** p<0.01, *** p<0.001).