Figure 7. Effect of short-term rifampin treatment on the plasma concentrations of vitamin D metabolites.

Plasma samples were collected before (pre-RIF) and after (post-RIF) rifampin administration (300 mg, PO, 6 days). Paired comparisons were conducted to show the direct effect of rifampin on the levels of four metabolites in each individual. Statistical analysis was conducted using a paired t-test; a p value less than 0.05 indicates significance.