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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Neuroscience. 2013 Feb 9;237:223–231. doi: 10.1016/j.neuroscience.2013.01.068

Figure 1. Sex Differences in NAD+ Levels.

Figure 1

NAD+ levels were analyzed 60 minutes after ischemic onset in male, female, and ovx female WT (A) and PARP-1−/− (B) mice (n=8/group: p<0.05). Stroke-induced NAD+ depletion was seen in WT males, and WT Ovx females. PARP-1−/− males maintained their NAD+ levels, while PARP-1−/− females experienced a loss of NAD+ after stroke. NAD+ levels were analyzed 30 minutes after reperfusion in male, female, and Ovx female WT (C) and PARP-1−/− (D) mice (n=8/group: p<0.05). Stroke-induced NAD+ depletion was seen in WT males. PARP-1−/− males maintained their NAD+ levels in all sexes after stroke.