Table 7.
Comparisons of myotonic dystrophy to controls on measures of fractional anisotropy (FA) and mean diffusion (MD) in individual white matter tracts.
| Control (n = 15) | Myotonic Dystrophy (n =16) | Statistical tests | |||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Mean | SD | Mean | SD | t | p | Effect size (Cohen’s d) | |
| Fractional Anisotropy (FA) | |||||||
| Corticospinal tract | .578 | .024 | .577 | .025 | 0.08 | .94084 | .05 |
| Inferior Longitudinal Fasciculus (ILF) | .476 | .021 | .433 | .022 | 5.50 | <.00001 | 2.0 |
| Superior Longitudinal Fasciculus (SLF) | .474 | .018 | .426 | .028 | 5.61 | <.00001 | 2.0 |
| Uncinate Fasciculus | .394 | .026 | .346 | .017 | 5.99 | <.00001 | 2.2 |
| Mean Diffusivity (MD) | |||||||
| Corticospinal tract | .770 | .014 | .802 | .025 | 4.50 | .00010 | 1.6 |
| Inferior Longitudinal Fasciculus (ILF) | .841 | .020 | .919 | .048 | 5.87 | <.00001 | 2.1 |
| Superior Longitudinal Fasciculus (SLF) | .767 | .019 | .843 | .042 | 6.39 | <.00001 | 2.3 |
| Uncinate Fasciculus | .848 | .021 | .927 | .026 | 9.44 | <.00001 | 3.3 |
Note: Mean Diffusivity values are ×10−6 mm2/second; Mean values represent the average of the right and left tracts.