TABLE 3.

Hazard ratios and 95% confidence intervals of hypertension according to vitamin D receptor gene polymorphisms

	BsmI polymorphism				FokI polymorphism
	bb	bB	BB	P(a)	FF	Ff	ff	P
N of cases / total	182 / 346	265 / 420	80 / 132		208 / 347	229 / 407	85 / 131
Age and race adjusted model	1.00 (reference)	1.36 (1.12–1.64)	1.27 (0.98–1.65)	0.01	1.00 (reference)	0.94 (0.78–1.14)	1.23 (0.95–1.58)	0.30
	1.00 (reference)	1.34 (1.12–1.60)			1.00 (reference)		1.27 (1.00–1.60)
Multivariable model 1(b)	1.00 (reference)	1.31 (1.08–1.59)	1.25 (0.96–1.63)	0.02	1.00 (reference)	0.92 (0.76–1.12)	1.23 (0.95–1.59)	0.34
	1.00 (reference)	1.29 (1.08–1.55)			1.00 (reference)		1.28 (1.01–1.63)
Multivariable model 2(c)	1.00 (reference)	1.27 (1.04–1.55)	1.19 (0.90–1.56)	0.07	1.00 (reference)	0.87 (0.72–1.06)	1.23 (0.94–1.61)	0.50
	1.00 (reference)	1.25 (1.04–1.51)			1.00 (reference)		1.32 (1.03–1.70)

^(a)P values were derived from additive effect model in which wild-type homozygotes, heterozygotes, and variant homozygotes were coded as 0, 1, and 2, respectively.

^(b)Multivariable model 1 additionally adjusted for cigarette smoking status (never, past, current), alcohol consumption (none, monthly, weekly, daily), exercise (none, 1–3/m, 1/w, 2–4/w, 5–6/w, daily), multivitamin use (never, past, current).

^(c)Multivariable model 2 adjusted for all covariates in model 1 plus body mass index (continuous), history of diabetes (yes, no), and history of hypercholesterolemia (yes, no).