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Characteristics of non-targeted IONP-Gem and uPAR-targeted ATF-IONP-Gem
| Samples | Coupling molar ratioa (IONPs:ATF:Gem) | Hydrodynamic particle sizeb (nm) |
|---|---|---|
| IONPs | 22.2 | |
| IONP-Gem | 1:0:580 | 49.9 |
| ATF-IONP-Gem | 1:13:570 | 65.9 |
Amount of ATF peptides or gemcitabine molecules were evaluated by Bradford assay or HPLC analysis, respectively,
Particle size was measured by Zetasizer Nano ZS90.
