Table 1.
Characteristic | Baseline (n = 66) |
---|---|
Age, mean (range), yr |
49 (18 – 74) |
Male : Female, n (%) |
15 (23) : 51 (77) |
White* |
58 (88) |
PAH etiology, n (%) | |
Idiopathic/heritable |
33 (50) |
Collagen vascular disease |
13 (20) |
Congenital heart disease |
17 (26) |
HIV |
3 (5) |
Background PAH therapy, n (%) | |
Endothelin receptor antagonist |
56 (85) |
Phosphodiesterase-5 inhibitor |
46 (70) |
Both |
39 (59) |
None |
3 (5) |
WHO functional class, n (%) | |
II |
38 (58) |
III |
28 (42) |
6-minute walk distance, mean ± SD, m |
395 ± 79 |
Borg dypnea score, mean ± SD |
3.4 ± 2.1 |
Iloprost dose, n (%) | |
2.5 μg |
4 (6) |
5.0 μg |
62 (94) |
Iloprost frequency | |
< 6 times per day |
25 (38) |
≥ 6 times per day | 41 (62) |
* n = 58 (8 missing).