Fig. 4.
Markers of liver injury were similar in high-fat (HF)-diet-fed C57BL6 and 129/SVJ mice. Serum and liver tissues were harvested from BL6 and 129/SVJ mice after a 6-month treatment with control diet (Ctr, n = 11/group) or HF diet (HF, n = 26/group). (A) Serum alanine aminotransferase (ALT); (B) aspartate aminotransferase (AST); (C) hepatic caspase 3/7 activity. Terminal deoxynucleotidyl transferase-mediated dUTP nick-end labelling -positive cells in BL6 (D) and 129/SVJ (E). Results are mean (SEM). *P<0.05 vs respective Ctr.