Table 1.
Types | Chemical composition | Common NSAIDs |
---|---|---|
Salicylates | Derivatives of 2-hydroxybenzoic acid (salicylic acid) | Aspirin, diflunisal, and salsalate |
| ||
Propionic acid derivatives or “profens” | Derivatives of arylacetic acids | Ibuprofen, dexibuprofen, ketoprofen, dexketoprofen, naproxen, fenoprofen, flurbiprofen, oxaprozin, and loxoprofen |
| ||
Acetic acid derivatives | Derivatives of acetic acids | Indomethacin, diclofenac, nabumetone, tolmetin, sulindac, etodolac, and ketorolac |
| ||
Enolic acid derivatives or oxicams | Derivatives of 4-hydroxy benzothiazine heterocycle | Piroxicam, isoxicam, meloxicam, tenoxicam, droxicam, and lornoxicam |
| ||
Fenamic acid derivatives or fenamates | Derivatives of anthranilic acid | Mefenamic acid, flufenamic acid, tolfenamic acid, and meclofenamic acid |
| ||
Phenylpyrazolones | Derivatives of 1-aryl-3,5- pyrazolidinedione |
Phenylbutazone, oxyphenbutazone |
| ||
COX-2 selective inhibitors | Diaryl-5-membered heterocycles | Celecoxib, rofecoxib, and valdecoxib |
| ||
Anilides and sulphoanilides | Acetamides of aniline with or without a 4-hydroxy or 4-alkoxy group | Acetaminophen, phenacetin, and nimesulide |