Table 1.
Baseline characteristics of 57 older subjects with bipolar depression
| Variable | Value |
|---|---|
| Age, years, mean (SD), [range] | 66.5 (6.7), [60–90] |
| Female, n (%) | 23 (40.4) |
| Race, n (%) | |
| White | 49 (86.0) |
| Black | 7 (12.3) |
| Asian | 1 (1.7) |
| Hispanic ethnicity, n (%) | 2 (3.5) |
| Education, years, mean (SD), [range] | 14.5 (2.7), [8–23] |
| Living alone, n (% | 26 (45.6) |
| Marital status, n (%) | |
| Single, never married | 2 (3.5) |
| Married | 26 (45.7) |
| Separated | 1 (1.7) |
| Divorced | 23 (40.3) |
| Widowed | 5 (8.8) |
| Uses health aide or live-in help, n (%) | 4 (7.0) |
| Type of bipolarity, n (%) | |
| BD-I 44 | (77.2) |
| BD-II | 13 (22.8) |
| Age at onset of illness, years | |
| Mean (SD) | 30.8 (16.0) |
| Range (median) | 7–67 (22) |
| Past suicide attempt, n (%) | 21 (36.8) |
| HAM-D24 score, mean (SD) | 27.1 (6.7) |
| MADRS score, mean (SD) | 25.3 (8.3) |
| CGI-BP, mean (SD) | |
| Severity: mania | 1.3 (0.6) |
| Severity: depression | 4.6 (0.8) |
| Severity: overall | 4.6 (0.8) |
| Past substance abuse, n (%) | 22 (38.6) |
| MMSE, mean (SD), [range]a | 28.7 (1.7), [22–30] |
| CIRS-G cumulative score, mean (SD), [range] |
9.5 (4.7), [2–21] |
| Concomitant maintenance BD treatments, n (%) |
|
| Lithium | 6 (10.5) |
| Divalproex/valproate | 9 (15.8) |
| Any anticonvulsant | 19 (33.3) |
| Antipsychotics | 18 (31.6) |
| Antidepressants (at baseline) | 34 (59.7) |
BD = bipolar disorder; BD-I = bipolar I disorder; BD-II = bipolar II disorder; HAM-D24 = 24-item Hamilton Rating Scale for Depression; MADRS = Montgomery–Åsberg Rating Scale; CGI-BP = Clinical Global Impression–Bipolar version; MMSE = Mini-Mental State Examination; CIRS-G = Cumulative Illness Rating Scale for Geriatrics.
a
(n = 56, 1 patient refused).