Figure 1.

Growth inhibiting effects of RPM on pancreatic cancer cell lines PC-2 and PANC-1.

Notes: Pancreatic cancer cells were treated with RPM (0, 10, 20, 30, 40, 50, 60, and 70 nmol/L) for 48 hours. Cell viability was determined by the MTT method. This assay was performed in triplicate. A dose-dependent inhibition of cell growth could be observed (P < 0.05, ANOVA analysis).

Abbreviations: ANOVA, analysis of variance; MTT, 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; RPM, rapamycin.