Table 3.

Factors affecting the amount of home help services (hours per week)

Percentage of variance accounted for	R = 0.436, R2 = 0.190, P < 0.001
Significant predictors in the final regression model	β	β (95% CI)	P
Intercept	−5.116	−8.279, −1.954	0.002
Sex (male = 0, female = 1)	−0.913	−1.735, −0.091	0.030
Solitary living at the respective assessment (no = 0, yes = 1)	2.808	2.001, 3.616	<0.001
ChEI dosea	−0.021	−0.039, −0.002	0.030
Time in months from the start of ChEI therapy	0.032	0.001, 0.062	0.041
MMSE score at the respective assessment	0.133	0.060, 0.205	<0.001
IADL score at the respective assessment	0.305	0.199, 0.412	<0.001
PSMS score at the respective assessment	0.343	0.213, 0.474	<0.001
Number of medications at baseline	−0.247	−0.372, −0.121	<0.001

Notes: APOE genotype, type of ChEI agent, age at onset or at baseline, years of education, rate of change in MMSE, IADL, or PSMS scores, and the interaction term “sex × solitary living” were not significant. β values were unstandardized and are expressed per 1 unit increase for continuous variables and for the condition present for dichotomous variables.

^aMean percentage of the maximum recommended dose, ie, 10 mg of donepezil, 12 mg of rivastigmine, or 24 mg of galantamine.

Abbreviations: APOE, apolipoprotein E; ChEI, cholinesterase inhibitors; CI, confidence interval; IADL, Instrumental Activities of Daily Living scale; MMSE, Mini-Mental State Examination; PSMS, Physical Self-Maintenance Scale.