Figure 2.

Effect of cediranib, sunitinib, and imatinib on U251 cellular migration and invasion. (A) Migration was measured at 48 hours by wound healing migration assay. The relative migration distance was calculated as indicated in Materials and Methods section and the results are expressed as the means ± SD. (B) Invasion was assessed by Matrigel invasion assay. The results were expressed in relation to the DMSO control (considered as 100% of invasion) as the mean percentage of invasion ± SD. (C) Representative pictures of invasion assay (x40 magnification).