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. 2013 Mar 28;9(3):e1003272. doi: 10.1371/journal.ppat.1003272

Figure 5. Hantavirus-infection inhibits NK cell-mediated activation of caspase 3 in endothelial cells.

Figure 5

Prevention of caspase 3 activation in infected cells exposed to IL-2-activated NK cells. (A) Representative flow cytometry histogram showing cellular caspase 3-activity in uninfected and HTNV-infected HLA class I blocked endothelial cells with and without co-incubation with IL-2-activated NK cells. Data shown is one representative donor out of six. (B) Percentage of caspase 3-positive uninfected and HTNV-infected endothelial cells after co-incubation with IL-2-activated NK cells analyzed by flow cytometry. Data shown represent two independent experiments from six donors. Two-tailed Student's t test was used for statistical evaluation; ** p<0.01.