Table 5. Enriched pathway terms when comparing candidate genes to the whole genome using GeneMerge1.2.
Pathway term | Description | Pop-frec | CR-frec | ratio | P value |
bta04510 | Focal adhesion | 192/27430 | 93/9829 | 1.35 | 0.0464 |
bta03040 | Spliceosome | 126/27430 | 67/9829 | 1.48 | 0.0107 |
bta04270 | Vascular smooth muscle contraction | 122/27430 | 66/9829 | 1.51 | 5.94E-3 |
bta05322 | Systemic lupus erythematosus | 189/27430 | 92/9829 | 1.36 | 0.0402 |
bta04080 | Neuroactive ligand-receptor interaction | 318/27430 | 155/9829 | 1.36 | 3.00E-4 |
bta04010 | MAPK signaling pathway | 266/27430 | 131/9829 | 1.37 | 9.80E-4 |
bta01100 | Metabolic pathways | 1081/27430 | 471/9829 | 1.22 | 1.00E-5 |
This table describes significant pathway terms over-represented in core regions based on GeneMerge1.2 software. Pop-frec describes the frequency of genes in the population with this pathway, and CR-frec describes the frequency of genes in the core regions with this pathway. Ratio is calculated by the comparison of a term within the core regions to that in genome wide. P value here is a Bonferroni corrected P value.