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. 2013 Mar 28;8(3):e60440. doi: 10.1371/journal.pone.0060440

Table 5. Enriched pathway terms when comparing candidate genes to the whole genome using GeneMerge1.2.

Pathway term Description Pop-frec CR-frec ratio P value
bta04510 Focal adhesion 192/27430 93/9829 1.35 0.0464
bta03040 Spliceosome 126/27430 67/9829 1.48 0.0107
bta04270 Vascular smooth muscle contraction 122/27430 66/9829 1.51 5.94E-3
bta05322 Systemic lupus erythematosus 189/27430 92/9829 1.36 0.0402
bta04080 Neuroactive ligand-receptor interaction 318/27430 155/9829 1.36 3.00E-4
bta04010 MAPK signaling pathway 266/27430 131/9829 1.37 9.80E-4
bta01100 Metabolic pathways 1081/27430 471/9829 1.22 1.00E-5

This table describes significant pathway terms over-represented in core regions based on GeneMerge1.2 software. Pop-frec describes the frequency of genes in the population with this pathway, and CR-frec describes the frequency of genes in the core regions with this pathway. Ratio is calculated by the comparison of a term within the core regions to that in genome wide. P value here is a Bonferroni corrected P value.