Table 4. Chromosome numbers and copy numbers of the tumorigenic clone cen3tel PD166, and at subsequent generations PD617 and PD1014.
Cen3tel clones |
PD166 |
PD617 |
PD1014 |
---|---|---|---|
Chromosome no. ± SD |
76 ± 3 |
72 ± 4 |
73 ± 1 |
No. of metaphases |
20 |
17 |
20 |
Chromosomes | Copy number (% clonal) | ||
1 |
2 (95) |
2 (65) |
1 (80) |
2 |
3 (70) |
3 (76) |
2 (60) |
3 |
1 (95) |
1 (82) |
1 (95) |
4 |
2 (95) |
2 (65) |
2 (100) |
5 |
3 (80) |
2 (65) |
2 (90) |
6 |
2 (95) |
2 (59) |
1 (75) |
7 |
2 (90) |
3 (65) |
3 (60) |
8 |
3 (80) |
4 (71) |
3 (60) |
9 |
3 (85) |
1 (94) |
1 (100) |
10 |
2 (70) |
2 (88) |
2 (85) |
11 |
4 (65) |
3 (65) |
3 (90) |
12 |
3 (80) |
3 (71) |
3 (80) |
13 |
2 (100) |
2 (88) |
2 (100) |
14 |
3 (95) |
3 (82) |
3 (100) |
15 |
2 (75) |
2 (76) |
2 (100) |
16 |
2 (65) |
3 (53) |
3 (60) |
17 |
3 (100) |
3 (59) |
3 (90) |
18 |
3 (65) |
3 (71) |
3 (75) |
19 |
4 (90) |
3 (59) |
3 (80) |
20 |
4 (95) |
3 (53) |
4 (65) |
21 |
2 (65) |
2 (82) |
2 (95) |
22 |
2 (80) |
2 (82) |
2 (85) |
X |
4 (85) |
3 (35) |
3 (70) |
Y |
0 |
0 |
0 |
der(1;3) |
1 (100) |
1 (88) |
1 (95) |
der(3;1) |
1 (90) |
1 (76) |
1 (95) |
der(3;10) |
1 (95) |
1 (71) |
1 (95) |
der(6;22) |
1 (80) |
1 (94) |
1 (100) |
der(9p) |
1 (100) |
1 (76) |
1 (95) |
der(4) |
1(100) |
1(82) |
1 (100) |
der(10) |
1 (85) |
1 (65) |
1 (95) |
der(7) |
1 (80) |
1 (65) |
1 (75) |
der(1q) |
1 (75) |
1 (6) |
1 (5) |
der(8q) |
1 (45) |
1 (12) |
1 (50) |
i(5p) |
1 (85) |
1 (59) |
- |
der(6p) |
1 (85) |
- |
- |
der(16;3) |
1 (85) |
- |
- |
der(12;14) |
1 (75) |
- |
- |
der(10;16) |
1 (55) |
- |
- |
der(9q) |
- |
1 (88) |
1 (100) |
der(5;9) |
- |
1 (82) |
1 (100) |
der(15;1) |
- |
1 (71) |
1 (100) |
der(17;5) |
- |
1 (71) |
1 (35) |
der(6;3) |
- |
1 (65) |
1 (90) |
der(1;12) |
- |
1 (6) |
1 (55) |
der(8;5) |
- |
1 (6) |
1 (55) |
der(1;5) |
- |
1 (6) |
1 (55) |
der(1p;12) |
- |
1 (76) |
- |
der(6) |
- |
- |
1 (75) |
der(17;8) |
- |
- |
1 (70) |
der(2) | - | - | 1 (55) |