Table 1.

Baseline values before treatment for males in non-treated and Pioglitazone-treated groups after prenatal and early postnatal exposure to maternal high fat diet.

	Non-treated	Pioglitazone treated	P value
Body weight (gm)	38.4 ± 3.5	39.8 ± 4.7	0.6
VAT as determined by CT (% from total area)	28.7 ± 5.7	34.5 ± 2.9	0.4
SAT as determined by CT % from total area)	8.3 ± 1.3	8.9 ± 1.8	0.7
Liver/spleen radiodensity (HU)	0.7 ± 0.04	0.6 ± 0.02	0.6
Triglyceride (mmol/L)	2.3 ± 0.2	3.1 ± 0.2*	0.01
Fasting glucose (mg/dL)	178 ± 11.5	164 ± 11.0	0.4
Fasting insulin(ng/mL)	0.8 ± .02	1.3 ± 0.2	0.1
HOMA-IR	5.8 ± 2	12 ± 3.2	0.2

Data are means ± SEM. VAT – visceral adipose tissue, SAT – subcutaneous adipose tissue, HOMA-IR – homeostasis model assessment of insulin resistance.

^*indicate statistically significant difference between the groups (P<0.05.)