Figure 6. Effect of rosiglitazone on expression of galectin mRNA in lean and DIO mice.
Mice were fed regular chow (Lean) or HFD (DIO) for 17 weeks, with or without Rosi in the diet during the last 4 weeks. Expression of Gal-1 (A), Gal-3 (B), Gal-9 (C) and Gal-12 (D) was evaluated in VAT and SAT of Lean (open bars), Lean+Rosi (hatched bars), DIO (black bars) and DIO+Rosi (grey bars) by qPCR. Data are expressed as fold increase over Lean mice in either VAT or SAT using the ΔΔct method. Data are mean +/− SEM of 10 mice per group. *p<0.05, **p< 0.01,***p< 0.001 versus respective lean group; op<0.05 versus respective DIO without Rosi.