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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Breast Cancer Res Treat. 2013 Feb 28;138(2):395–406. doi: 10.1007/s10549-013-2464-7

Table 2.

Characteristic of Mammary Tumors from Ad libitum-fed (AL), Chronic Calorie Restricted (CCR) and Intermittent Calorie Restricted (ICR) TGF-α female mice

AL (42)# CCR (44) ICR (45)
Age of MT detection (weeks) 57.5±1.9a 74.5±1.6b 82.0±0.0b
% of mice in group with MT
(number with MT/total mice)
66.7% (28/42)c 52.3% (23/44)d 4.4% (2/45)e
MTs weight (g) 0.42±0.07* 0.75±0.24 0.051
Number of MTs/mouse 1.54±0.19
1-5*
1.70±0.16
1-3
1.00±0.00
1
Total number of MTs (%) 40 39 2
 Low grade and a carcinoma in situ 0 (0%) 2 (5 %) 0 (0%)
 Grade 2 28 (70%) 23 (59%) 2 (100%)
 Grade 3 10 (25 %) 12 (31%) 0 (0%)
 Grade 4 2 (5 %) 2 (5 %) 0 (0%)
#

number in parentheses is final n value.

Values are mean ± SE

a, b

Values within a row with different superscript letters are significantly different by Chi-square analysis. P<0.01

c, d, e

Values within a row with different superscript letters are significantly different by Chi-square analysis: P<0.0001

*

Values within a row with different superscript star are significantly different by t-test (only AL and CCR, but not ICR –Only one mouse with weighed tumor).