Table 2.
Clinical characteristics of patients with false-negative 18F-FDOPA PHEO/PGL.
| Patient | Institution | Genetic status | Total number of lesions | Number of FDOPA+ lesions | Lesions missed by 18F-FDOPA PET | ||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| Tumour location | Origin | Size (mm) | 18F-FDG PET | Gold standard | |||||
| 1 | Timone | Sporadic | 1 | 0 | Carotid body | Parasympathetic | 30 | nd | Surgery |
| 2 (fig 1) | Timone | SDHD | 8 | 4 | Adrenal | Sympathetic | 9 | + | Surgery |
| Abdo aortocaval | Sympathetic | 26 | + | Surgery | |||||
| Abdo lateral caval | Sympathetic | 17 | + | Surgery | |||||
| Abdo iliac bifucation | Sympathetic | 6 | + | Surgery | |||||
| 3 | Timone | SDHD | 8 | 2 | Abdo pre-aortic | Sympathetic | 21 | + | Surgery |
| Abdo lateral aortic | Sympathetic | 18 | + | Surgery | |||||
| 4 (fig 2) | Timone | SDHD | 7 | 5 | Cervical vagal | Parasympathetic | 5 | − | Imaging |
| Abdo lateral aortic | Sympathetic | 14 | + | Imaging | |||||
| 5 (fig 3) | Timone | SDHB | 2 | 0 | Abdo lateral-aortic | Sympathetic | 28 | + | Surgery |
| Abdo pre-aortic (Zuckerkandl) | Sympathetic | 13 | + | Surgery | |||||
| 6 | Timone | SDHB | 1 | 0 | Abdo lateral aortic | Sympathetic | 45 | + | Imaging |
| 7 (fig 4) | NIH | SDHD | 4 | 2 | Adrenal | Sympathetic | 27 | + | Surgery |
| Adrenal | Sympathetic | 34 | + | Surgery | |||||
| 8 (fig 5) | NIH | SDHD | 10 | 9 | Post mediastinum | Sympathetic | 30 | + | Imaging |
| 9 | NIH | SDHB | 1 | 0 | Abdo lateral aortic | Sympathetic | 15 | + | Surgery |
Abbreviations: nd: not done; Abdo: abdominal.