Skip to main content
. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Obesity (Silver Spring). 2013 Feb;21(2):353–360. doi: 10.1002/oby.20045

Figure 4. Development of diet induced obesity in high activity (HA) and low activity (LA) rats.

Figure 4

(A) HA and LA rats selected for high fat (HF; HA, N = 17; LA, N = 10) and low fat (LF; HA, N = 16; LA, N = 9) feeding for 10 weeks showed no significant differences in ambulatory SPAINT at selection (HA, W = 170, P < 0.001; LA, W = 144, P < 0.001). (B) Cumulative caloric intake. (C) Fat mass gain (ΔFM). (D) Lean mass gain (ΔLM). Line: P ≤ 0.05 for main effect of phenotype (See Results). (E) Severity of obesity as measured by ratio of fat to lean mass gain (ΔFM/ΔLM) is lower in HA compared to LA rats. For plots C, D and E, the line indicates P ≤ 0.05 for pairwise comparisons corrected for multiple comparisons (See Methods, Statistical Analysis).