Table 1.

Breast Cancer Natural History Input Parameters Used in UWBCS Model Calibration [24]

Parameter Name	Best fit in the original combined race UWBCS model	Sampled Parameter Values
LMP Fraction	0.42	0.00, 0.10, 0.20, 0.30, 0.40, 0.50, 0.60
LMP Dwell Time	2	1, 2, 3
Onset Proportion	0.90	0.80, 0.85, 0.90, 0.95, 1.00
APC Lag	3	1, 3, 5, 7
Mean Growth	0.12	0.01, 0.05, 0.10, 0.15, 0.20
Variance Growth	0.012	0.006, 0.010, 0.040, 0.070, 0.100
Percent Aggressive	0.01	0.00, 0.01, 0.02, 0.03, 0.04, 0.05
Percent Highly Aggressive	0.02	0.00, 0.01, 0.02, 0.03, 0.04, 0.05

Abbreviations: UWBCS, University of Wisconsin Breast Cancer Simulation; LMP, limited malignant potential; APC, Age-Period-Cohort