Figure 5. Curcumin-induced Nrf2-binding activity to ARE.
A, Nrf2-binding activity to ARE: EMSA using the ARE probe in nuclear extracts of cortical rat neurons. The ARE-protein binding complexes (arrow) are indicated. B, semiquantitative analyses of Nrf2-binding activity to ARE. Bars represent mean±SEM (n = 6–8 for each group). *p<0.05 vs sham, △p<0.05 vs vehicle.