Ascorbic acid and dehydroascorbic acid transport across rat intestine. Rats were gavaged with 12 mg of dehydroascorbic acid (▴), ascorbic acid (♦), or PBS vehicle (■). Post-gavage plasma ascorbic acid levels were determined by HPLC, as described under “Experimental Procedures.” Data represent the mean ± S.D. of at least 10 rats per gavage treatment. When compared with vehicle and ascorbic acid gavage, time-diet interactions reached significance at 60 min post-DHA gavage (*, p < 0.01 two-tailed paired t test).