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. 2013 Feb 13;288(13):9153–9164. doi: 10.1074/jbc.M112.440354

FIGURE 1.

FIGURE 1.

MB increases OCR and decreases ECAR in U87 cells. A, OCR of human female primary astrocytes and U87 glioma cells is shown. Although U87 cells have a higher base-line OCR, both were able to obtain a similar maximum OCR upon FCCP treatment. B, ECAR of female primary astrocytes and U87 glioma cells is shown. U87 cells maintained a greater ECAR compared with human female astrocytes. C, effects of MB at concentrations of 100 nm, 1 μm, and 10 μm on U87 cell OCR are shown. D, effects of MB at concentrations of 100 nm, 1 μm, and 10 μm on U87 cell ECAR are shown. E, MB significantly increased U87 cell OCR at concentrations of 1 and 10 μm. F, MB significantly decreased U87 cell ECARs at concentrations of 1 and 10 μm. * indicates p < 0.05 by 1-way ANOVA and Tukey's post-hoc test.