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. 2013 Feb 13;288(13):9153–9164. doi: 10.1074/jbc.M112.440354

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© 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 2. — Chronic MB treatment alters cellular bioenergetics. A, shown are OCRs of U87 cells treated for 1 and 2 days with 10 μm MB. MB was withdrawn 1 h before analysis. B, shown are ECARs of U87 cells treated for 1 and 2 days with 10 μm MB. MB was withdrawn 1 h before analysis. C, 10 μm MB decreased OCR in U87 cells after 1 and 2 days of treatment. D, 10 μm MB decreased ECARs in U87 cells after 1 and 2 days of treatment. * indicates p < 0.05 by one-way ANOVA and the Tukey's post-hoc test. E, MB increased cell ATP after 2 days of treatment. F, MB reduced lactate production. * indicates p < 0.05 by unpaired t test.