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. 2013 Feb 12;288(13):9293–9302. doi: 10.1074/jbc.M113.455816

FIGURE 6.

FIGURE 6.

cAMP levels induced by EP2 activation in rat primary microglia. Rat microglia pretreated with vehicle or 0.1 or 0.3 μm TG4-155 for 30 min were incubated with different concentrations of PGE2 or butaprost for 2 h. TG4-155 caused a concentration-dependent shift to the right in the PGE2 or butaprost concentration-response curve in resting state microglia (A) and classically activated microglia (B). Data points represent mean ± S.E. (error bars) from a single experiment run in triplicate.