TABLE 1.
Clinical and laboratory characteristics of patients (ranges shown in parentheses)
| Wt-NPM1 | Mt-NPM1 | p | |
|---|---|---|---|
| No. of patients | 14 | 8 | |
| Sex | |||
| Male | 5 | 5 | |
| Female | 9 | 3 | 0.60 |
| Median age (years) | 54.5 (18–78) | 62 (44–76) | |
| FAB classification | |||
| M0 | 1 | 0 | |
| M1 | 2 | 2 | |
| M2 | 4 | 2 | |
| M4 | 2 | 2 | |
| M5 | 2 | 2 | |
| M6 | 3 | 0 | 0.50 |
| TLD+ | 6 | 4 | 0.50 |
| Median white blood cell count/μl | 7300 (1300–556,000) | 47,500 (1700–114,700) | 0.10 |
| Median lactate dehydrogenase level | 647 (203–5325) | 669 (270–2391) | 0.07 |
| Median bone marrow cell count/μl | 337,000 (9000–738,000) | 475,000 (34,900–769,000) | 0.10 |