The plasma (A) IL-1β and (B) TNF-α levels and their change percentages (%) (C), (D) in patients with schizophrenia after 11 weeks of treatment with risperidone (Risp)+Placebo or Risp+add-on dextromethorphan (DM) (60 mg/day). Plasma samples were collected and analyzed at 0, 2, 4, 8, and 11 weeks. *p < 0.05, **p < 0.01, ***p < 0.001 vs. week 0 data within same group (repeated-measures ANOVA with Newman-Keuls post test).